Description

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Dosage and administration

Dosage adjustments should be based on the patient’s clinical response.It may occasionally be necessary to exceed the usual dosage recommended below in cases of more severe pain or in those patients who have become tolerant to the analgesic effect of opioids. If pain is constant, the opioid analgesic should be given at regular intervals on an around-the-clock schedule. ENDOCET tablets are given orally.

Endocet 5 mg/325 mg;

Endocet 7.5 mg/500 mg;

Endocet 10 mg/650 mg
The usual adult dosage is one tablet every 6 hours as needed for pain. The total daily dose of acetaminophen should not exceed 4 grams.

Endocet 7.5 mg/325 mg;

 

Endocet 10 mg/325 mg

The dose for adult is one tablet every six hours needed for pain. The total daily dose of acetaminophen should not exceed 4 grams.

Power	Max.Daily Dose
End:5 mg/325 mg	12 Tablets
End: 7.5 mg/325 mg	8 Tablets
End: 7.5 mg/500 mg	8 Tablets
End: 10 mg/325 mg	6 Tablets
End:10 mg/650 mg	6 Tablets

 

Side effects

• Grapefruit juice
• Herbal remedies
• General anesthetics (drugs used during surgery)
• Benzodiazepines (drugs used to help you sleep or that help reduce anxiety)
• Drugs used to treat serious mental or emotional disorders (such as schizophrenia)
• Antihistamines (drugs used to treat allergies)
• Anti-emetics (drugs used for the prevention of vomiting)
• Drugs used to treat muscle spasms and back pain
• Warfarin (such as Coumadin) and other anticoagulants (used for prevention or treatmentof blood clots)
• Anti-retroviral drugs (used to treat viral infections)
• Anti-fungal drugs (used to treat fungal infections)
• antibiotic drugs (used to treat bacterial infections)
• some heart medication (such as beta blockers)

CONTRAINDICATIONS

These tablets should not be administered to patients with known hypersensitivity to oxycodone, acetaminophen, or any other component of this product. Oxycodone is contraindicated in any situation where opioids are contraindicated adding patients with significant respiratory depression (in unmonitored settings or the absence of resuscitative equipment) and patients with acute or severe bronchial asthma or hypercarbia. Oxycodone is contraindicated in the setting of suspected or known paralytic ileus.

Warnings

Even if you take ENDOCET as prescribed you are at a risk for opioid addiction, abuse and misuse. This can lead to overdose and death.When you take ENDOCET it must be swallowed whole. Do not cut, break, crush, chew, and dissolve the tablet. This can be dangerous and can lead to death or seriously harm you.You may get life-threatening breathing problems while taking ENDOCET.You should never give anyone your ENDOCET. They could die from taking it. If a person has not been prescribed ENDOCET, taking even one dose can cause a fatal overdose. This is especially true for children. If you took ENDOCET while you were pregnant, whether for short or long periods of time or in small or large doses, your baby can suffer life-threatening withdrawal symptoms after birth. This can occur in the days after birth and for up to 4 weeks after delivery. If your baby has any of the following symptoms:

• has changes in their breathing (such as weak, difficult or fast breathing)
• is unusually difficult to comfort
• has tremors (shakiness)
• has increased stools, sneezing, yawning, vomiting, or fever

Seek immediate medical help for your baby.Taking ENDOCET with other opioid medicines, benzodiazepines, alcohol, or other central nervous system depressants (including street drugs) can cause severe drowsiness, decreased awareness, breathing problems, coma, and death. WIKI

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