Buy GBL Online

Description

Buy GBL Online

Gamma butyrolactone is a chemical. People use it as medicine. Be careful not to confuse gamma butyrolactone (GBL) with gamma hydroxybutyrate (GHB).
Despite serious safety concerns and illegality, people take gamma butyrolactone for improving athletic performance, sleep, and sexual performance and pleasure. They also take it for relieving depression and stress, prolonging life, promoting clear thinking, causing relaxation, and release growth hormones. GBL is also used to trim fat and as a body- or muscle-builder. Some people take it as a recreational drug.
How does it work?
Gamma butyrolactone is converted in the body to gamma hydroxybutyrate (GHB) which affects several nerve pathways in the brain.

γ-Hydroxybutyrate, 1,4-Butanediol, and γ-Butyrolactone
γ-Hydroxybutyrate (GHB) and its synthetic precursor compounds, 1,4-butanediol (1,4-BD) and γ-butyrolactone (GBL), are Schedule I agents in the United States, and availability is restricted in numerous other countries. GHB is illegally purchased as an odorless and colorless liquid form or as an off-white powder that easily dissolves in liquids. When ingested, GHB stimulates dopamine release, leading to pleasurable effects such as euphoria, muscle relaxation, and heightened sexual desire.780,781 It also has CNS depressant effects, resulting in sedation and hypnosis. Because GHB was reported to enhance growth hormone release, it has been used by body builders and athletes as a steroid alternative. Athletes have used GHB as a sleep aid because they believe it promotes rapid recovery from vigorous repetitive competition. These properties and the availability of GHB in dietary supplements have led to growing recreational abuse of the drug. GHB has become popular as a euphorigenic club drug, most often used in combination with alcohol, and also with MDMA or cocaine, to “mellow” their adverse stimulant properties. Its rapid onset and hypnotic and short-term amnestic properties have resulted in the use of GHB for drug-facilitated sexual assault (date rape drug).715,716,772,782 It has been estimated that 4% of alleged sexual assault cases in the United States are positive for GHB.715,739,766,783
GHB is a naturally occurring substance produced in the brain. GHB is reversibly metabolized to GABA through multiple endogenous enzymes (Fig. 41.15).784-786 Illicit consumption of GHB, or the synthetic GHB precursor compound 1,4-BD or GBL, will promote GABA activity.786 In addition to increased metabolism to GABA, GHB has direct effects on the CNS by binding GHB-specific receptors and GABAB receptors.787-789 The latter are G-protein–coupled receptors distinct from the GABAA receptors for depressant drugs, such as benzodiazepines and barbiturates. Of note, patients with GHB overdose do not respond to the opioid antagonist naloxone or to the benzodiazepine antagonist flumazenil. Fomepizole, an inhibitor of ADH, is likely beneficial for patients who ingest 1,4-butanediol.790 GHB is suggested to increase dopamine concentrations in the substantia nigra, to potentiate the endogenous opioid system, and to mediate GABA transmission.786

USES & EFFECTIVENESS
Insufficient Evidence to Rate Effectiveness for…
• Causing relaxation.
• Increasing mental clarity.
• Relieving depression and stress.
• Prolonging life.
• Improving sexual performance and pleasure.
• Reducing fat.
• Releasing growth hormone.
• Improving athletic performance.
• Improving sleep.
• As a body-builder or muscle-builder.
• As a recreational drug.
• Other conditions.

Side Effects

Use of GBL, or the closely related gamma hydroxybutyrate (GHB) and butanediol (BD), has been linked to deaths and cases of serious side effects. These serious side effects include the inability to control the bowels, vomiting, mental changes, sedation, agitation, combativeness, memory loss, serious breathing and heart problems, fainting, seizures, coma, and death. The effects can be made worse by alcohol or narcotics such as morphine, heroin, and others. Long-term use may lead to withdrawal symptoms including insomnia, tremor, and anxiety.

SPECIAL PRECAUTIONS & WARNINGS
GBL is UNSAFE and should not be taken by anyone. Certain people, especially those with the following conditions, are at even more risk for side effects.
Pregnancy and breast-feeding: GBL is UNSAFE. If you take it while pregnant or breast-feeding, you will endanger yourself as well as your baby.
Irregular heartbeat: GBL can make this condition worse.
Epilepsy: GBL might cause seizures.
High blood pressure: GBL might make this condition worse.
Surgery: GBL can affect the central nervous system (CNS). There is concern that combining GBL with anesthesia and other medications used during and after surgery might slow down the CNS too much. GBL should not be used in the two weeks before a scheduled surgery.
INTERACTIONS
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AlcoholInteraction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Alcohol can cause sleepiness and drowsiness. Taking GBL along with alcohol might greatly increase sleepiness and drowsiness caused by alcohol. Taking GBL along with alcohol can lead to serious side effects. Do not take GBL if you have been drinking.
________________________________________
Amphetamines Interaction Rating: Moderate Be cautious with this combination. Talk with your health provider.
Amphetamines are drugs that can speed up your nervous system. GBL is changed in the body to GHB (gamma hydroxybutyrate). GHB can slow down your nervous system. Taking GBL along with amphetamines can lead to serious side effects.