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Dosage and Administration
The dose is 15 mg daily (7.5 mg b.i.d.). To achieve an optimal therapeutic response, at intervals of 2 to 3 days the dosage may be increased 5 mg per day, as needed. The maximum daily dosage should not exceed 60 mg per day. In clinical trials allowing dose titration, divided doses of 20 mg to 30 mg per day were commonly employed.The bioavailability of buspirone is increased when given with food as compared to the fasted state
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Common side effects of Quaaludes include:
- Seizures and its depressant effects include reduced heart rate and respiration.
- Abdominal cramps
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Quaaludes should not be taken with alcohol or with other central nervous system depressants. This increases the depressant effects and depending on the doses taken it can be fatal. Do not drive or operate machinery while taking Quaaludes.
Contraindicated in women who are or may become pregnant; it’s safe use in children has not been established. Psychological dependence has occurred physical dependence has now reached alarming proportions & some authorities believe that potential for addiction & abuse are as serious as those of barbiturates & heroin. Should not be used for periods longer than 3 Mons furthermore it should not be prescribed for addiction-prone patients.
Patients on the drug should be warned against driving car or operating hazardous machinery. Used with caution in patients with depression or suicidal tendencies & those with liver dysfunction.
Coma has occurred after 2.4 g & death after. Most fatalities occur in persons who have also ingested ethanol. Abusers employ doses of 75 mg-2 g/day, with avg of about 725 mg. severe grand mal convulsions may occur after abrupt withdrawal from high doses. Info
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